Items will only ever break (dissapear) if they fail going from +5 -> +6 and so forth WITHOUT having an
immortal stat on them. Adding a stone to an item will never break it, or give it a minus durability stat (red stat). If you fail something while using an elixer it will go back to +0 unless it is +4 or higher with an
astral stat added. Lastly...Going from +4 -> +5 and so on without a
steady stat means there is a chance your weapon could obtain a minus durability stat (red stat) if it fails.
Covered question and then some.
If you just meant can the actualy 'seal of x' quality dissapear and not the whole item...no, it can't and sorry for wasting your time with that paragraph above =.=.
thx in advance 
Crumpets for Pres
... anyways thanks a lot