Playing games when using a dual monitor configuration can be a pain. The problem is that the mouse would move to the other monitor while playing the game, and you would lose control of the mouse for your game. To avoid this problem, I've written a small program, mostly based on David Antliff's switchscreen program. The idea is simply to lock your mouse in the monitor it currently is in. The tarball for this program is available at
http://www.cs.kent.ac.uk/~sm244/Jail.tar.gz . You can then simply bind a shortcut key to the program from your window manager.