well that usually happens when either the C++ runtime library or the sro executable file gets hosed up. They're each about equally as likely but it's easier to reinstall SRO so try that one first

or if U don't want to download the entire 500+ MB installer, I copied all 4 .exe files from the C:/program files/silkroad/ folder on my computer and put em in a zip file that you can download here:
http://download.yousendit.com/01952812445DFDDA
just unzip them and put them in the C:/program files/silkroad/ folder and tell it yes you want to replace the ones that are there.
It's possible a patch got currupted during download and patched one of your .exe files wrong so they don't run anymore and that's what would cause your problem. Hope that fixes it
