i do it like this:
i have a lot attack skills. probably too many, but i like them all
i mostly use only 3-4, but wich 3-4 that varies from mob to mob
my skilltabs look like,
F1-pve. F2-pvp. F3-buffs. F4-"unused skills"
so i decide what im going to hunt, then i put all the skills im going to use from F4 to F1 and use these. if i switch to another mob, i probably switch some skills as well.
why all the skills if i could just use soul+ghost pear?
cos i like them, cos soul+ghost isnt the fastest way to kill for a glaiver, cos i try to reduce the mana used so i can stay out longer, save money ect.