well, right now im lvl 34 and comparing my 250% nuke to my 200% throw, the nuke only does like 500-800 more dmg lol nuke does around 1.7-2.3k on things my lvl and throw does around 1.3-1.6k, nukes don't really greatly outdmg spear skills at lvl 3x but i kill flowers in 1 nuke so  
  
  for me lol, then again i dunno if my spear is as high of a dmg as a sos+3 can be cuz its 420 dmg and I havent seen higher, most i've seen was a 401... so yeah... you'll notice a difference at lvl 32+, a little bit anyways